Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene
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چکیده
منابع مشابه
Insertional mutation of the mouse Msx1 homeobox gene by an nlacZ reporter gene
We have generated a null allele of the mouse Msx1 homeobox gene by insertion of an nlacZ reporter gene into its homeobox. The sensitivity of beta-galactosidase detection permitted us to reveal novel aspects of Msx1 gene expression in heterozygous embryos, in particular in ectoderm and mesoderm during gastrulation, and in migrating neural crest cells. Homozygous mutant mice die at birth with fac...
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ژورنال
عنوان ژورنال: Mechanisms of Development
سال: 1997
ISSN: 0925-4773
DOI: 10.1016/s0925-4773(97)00065-8